Dr. Rhodes and Dr. Choi disagree over the final decision made by a patient suffering from a life-threatening heart condition. The pending lawsuit against Dr. Halstead continues to move forward and Sarah Reese and Dr. Zanetti scramble to save a patient with a misdiagnosed flesh-eating bacterial disease. Elsewhere, Dr. Manning treats a young girl diagnosed with a contagious bacteria, prompting her and Dr. Halstead to take action to avoid a major outbreak.