Investigates a murder in which two victims' faces are similarly mutilated; given a "Glasgow Smile." For the first time, Will contaminates a crime scene thinking he committed the first murder and an MRI shows he suffers from Advanced Encephalitis. But Hannibal intimidates the attending physician, Dr. Sutcliffe, who may be involved. With his fears fed by Hannibal, Will returns to Dr. Sutcliffe for more mental health tests, when the doctor is murdered.