When con artist Kenzi runs a "Shaman" scam, and does a spiritual cleanse of a human house where a bloody murder-suicide took place, she inadvertently brings home a vicious Fae spider whose venom turns people psychotic. After getting bitten by this nasty eight legger, both Bo and Kenzi's paranoia mounts – and the best friends begin to turn on each other in this haunted house homage, forcing romantic rivals Dyson and Lauren to put their differences aside and work together to find a way to kill the nasty arachnid... before Bo and Kenzi kill each other.