Spider-Man accepts Nick Fury's offer to train with S.H.I.E.L.D., and is put together with four other teenage superheroes: Nova (Sam Alexander), White Tiger (Ava Ayala), Power Man (Luke Cage) and Iron Fist (Danny Rand). Doctor Octopus sends the Frightful Four after Spider-Man again, and while Spider-Man doesn't initially get on with his new teammates, he has to learn to work alongside them to defeat the Frightful Four.