A mysterious woman, Mrs. Francis (Nina Foch), comes to Medicine Bow and asks the Virginian to take her to meet his friend, Michael O'Rorke (Michael Rennie), the former foreman of Shiloh, who now lives as an outlaw in the badlands. She believes her husband, who had been wrongly accused of murder, is hiding out with O'Rorke's gang. However, Mrs. Francis is not whom she claims and trouble follows.